Key result
Automated peritoneal dialysis was associated with a lower risk of technique failure (HR 0.58; 95% CI 0.34-0.98) compared to CAPD, with mortality benefits observed only in patients <65 years.
Why the study?
Does automated peritoneal dialysis improve overall mortality and technique failure compared to continuous ambulatory peritoneal dialysis in incident dialysis patients?
Population
282 incident peritoneal dialysis patients, divided into age <65 years and ≥65 years, Chinese cohort.
Comparison
Automated peritoneal dialysis (APD) vs Continuous ambulatory peritoneal dialysis (CAPD)
Design
Cohort
Authors
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Should not yet change PD modality selection; leaves open age-specific benefits in prospective RCTs.
Cohort (n=282)
Does automated peritoneal dialysis improve overall mortality and technique failure compared to continuous ambulatory peritoneal dialysis in incident dialysis patients?
Hazard Ratio: 0.72 (95% CI 0.44–1.2)
p-value: p=0.207
In younger Chinese incident peritoneal dialysis patients, automated peritoneal dialysis is associated with better patient and technique survival compared to continuous ambulatory peritoneal dialysis, though baseline confounding is possible.
Sun et al. (2011) conducted a cohort in Incident peritoneal dialysis (n=282). Automated peritoneal dialysis (APD) vs. Continuous ambulatory peritoneal dialysis (CAPD) was evaluated on Overall mortality (HR 0.72, 95% CI 0.44-1.20, p=0.207). Automated peritoneal dialysis was associated with a lower risk of technique failure (HR 0.58; 95% CI 0.34-0.98) compared to CAPD, with mortality benefits observed only in patients <65 years.
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