Key result
Urgent catheter ablation for serious tachyarrhythmias in octogenarians achieved a 100% acute success rate, comparable to elective ablation, with no significant difference in complications or mortality.
Why the study?
Does urgent radiofrequency catheter ablation improve outcomes safely compared to elective ablation in octogenarians with serious tachyarrhythmias?
Cohort (n=64)
No
Does urgent radiofrequency catheter ablation improve outcomes safely compared to elective ablation in octogenarians with serious tachyarrhythmias?
Absolute Event Rate: 100% vs 100%
p-value: p=1.00
Urgent catheter ablation for serious tachyarrhythmias in octogenarians is highly successful and safe, with long-term outcomes comparable to elective procedures.
Suggests urgent ablation may be a safe, effective option for highly selected octogenarians; leaves open.
BACKGROUND: Urgent catheter ablation is often required for various tachyarrhythmias; however, its efficacy and safety in elderly patients have not been fully elucidated. METHODS: This study included consecutive octogenarians who underwent urgent radiofrequency catheter ablation (RFCA) for various serious tachyarrhythmias (urgent group, n=28) that were life-threatening, hemodynamically deleterious, or provoking ischemia, and consecutive octogenarians who underwent elective RFCA (control group, n=36). The rate of a successful RFCA, complications, later arrhythmia recurrences, and mortality were compared between the groups. RESULTS: There was no significant difference in the breakdown of the targeted arrhythmias between the groups, and common-type atrial flutter was most often targeted in both the urgent group (57%) and the elective group (56%). Compared with the control group patients, the patients of the urgent group were older (84±3 vs. 82±2 years P=0.001), with a higher frequency of baseline heart disease (68% vs. 17%, P<0.001) and lower left ventricular ejection fraction (45%±15% vs. 68%±10%, P<0.001). The rates of acute success (100% vs. 100%, P=1.00) and later arrhythmia recurrences (4% vs. 14%, P=0.22) were comparable between the groups. Two patients in the urgent group and 2 in the elective group had procedure-related nonlethal complications (7% vs. 6%, P=1.00): groin hematoma in 2, pressure ulcer in 1, and CO2 narcosis in 1. There were no in-hospital deaths, and mortality during follow-up did not differ between the urgent and elective groups (6.0% vs. 3.9% per year, log-rank P=0.38). CONCLUSION: Even in octogenarian patients, urgent catheter ablation for serious tachyarrhythmias can be safely performed with a high success rate and acceptable prognosis.
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Takahashi et al. (2016) conducted a cohort in Serious tachyarrhythmias (n=64). Urgent radiofrequency catheter ablation vs. Elective radiofrequency catheter ablation was evaluated on Acute success of catheter ablation (p=1.00). Urgent catheter ablation for serious tachyarrhythmias in octogenarians achieved a 100% acute success rate, comparable to elective ablation, with no significant difference in complications or mortality.
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