What does this research mean for the field?

The global decline in under-5 mortality has slowed since 2016, with preterm birth complications and lower respiratory infections remaining the leading causes of death, putting many high-mortality countries at risk of missing Sustainable Development Goal targets. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To estimate cause-specific mortality among neonates and children under 5 years in 195 countries from 2000 to 2024.

June 6, 2026BMJ7 citations

Global Causes of Neonatal and Under 5 Mortality Estimates from 2000 to 2024

Systematic estimates of global causes of neonatal and under 5 mortality in 2000-24: secondary data analysis using bayesian multinomial logistic regression

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Authors

JPJamie Perin DPDavid Prieto-Merino AWAstha Wahi

Discussion

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Overview

Secondary data analysis estimates cause-specific mortality in neonates and under-5 children, highlighting slowed progress towards goals.

Key Points

To estimate cause-specific mortality among neonates and children under 5 years in 195 countries from 2000 to 2024.
Secondary data analysis using Bayesian multinomial logistic regression model
Inclusion of studies with empirical cause specific mortality for at least two causes
Models constructed based on vital registration and verbal autopsy data for mortality estimation
The leading cause of under-5 death was preterm birth complications with 0.82 million deaths, 6.17 deaths per 1000 live births
Followed by lower respiratory infections at 0.66 million deaths and intrapartum related events at 0.48 million deaths
Slowed decline in under-5 mortality since 2016, risking achievement of sustainable development goals.

Cite This Study

Perin et al. (2026) studied this question.

synapsesocial.com/papers/6a23b80771a5da9775e74521 https://doi.org/10.1136/bmj-2025-088686

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June 6, 2026BMJ7 citations

Global Causes of Neonatal and Under 5 Mortality Estimates from 2000 to 2024

Systematic estimates of global causes of neonatal and under 5 mortality in 2000-24: secondary data analysis using bayesian multinomial logistic regression

View Full Paper

Ask AI

Bookmark

Authors

JPJamie Perin DPDavid Prieto-Merino AWAstha Wahi

Discussion

Member takes

Overview

Secondary data analysis estimates cause-specific mortality in neonates and under-5 children, highlighting slowed progress towards goals.

Key Points

To estimate cause-specific mortality among neonates and children under 5 years in 195 countries from 2000 to 2024.
Secondary data analysis using Bayesian multinomial logistic regression model
Inclusion of studies with empirical cause specific mortality for at least two causes
Models constructed based on vital registration and verbal autopsy data for mortality estimation
The leading cause of under-5 death was preterm birth complications with 0.82 million deaths, 6.17 deaths per 1000 live births
Followed by lower respiratory infections at 0.66 million deaths and intrapartum related events at 0.48 million deaths
Slowed decline in under-5 mortality since 2016, risking achievement of sustainable development goals.

Cite This Study

Perin et al. (2026) studied this question.

synapsesocial.com/papers/6a23b80771a5da9775e74521 https://doi.org/10.1136/bmj-2025-088686

View Full Paper

Ask AI

Bookmark