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June 6, 2026Frontiers in NutritionOpen Access

Cholesterol, high-density lipoprotein, and glucose (CHG) index and incident impaired fasting glucose in Chinese adults: a retrospective longitudinal cohort study

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Authors

DYDuo YangRLRenzhe LinSLSen Li

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Overview

Retrospective cohort study evaluates the CHG index's association with incident IFG in Chinese adults, indicating its potential role in early diabetes identification.

Key Points

  • This study assesses the relationship between the CHG index and the risk of developing impaired fasting glucose in Chinese adults.
  • Analyzed data from 100,802 Chinese adults with normal fasting glucose.
  • Used multivariable Cox proportional hazards regression to evaluate relationships.
  • Applied restricted cubic splines to explore nonlinearity in associations.
  • 12,414 participants (12.32%) developed incident IFG during the follow-up.
  • Each one-unit increase in the CHG index significantly increased the risk of incident IFG (exact metrics not specified).
  • Nonlinear association detected with an inflection point at a CHG index of 5.259, marking a threshold effect.

Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/6a23b83e71a5da9775e747d6https://doi.org/10.3389/fnut.2026.1814747
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