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This study evaluates if combining the CURB-65 score with the platelet-to-lymphocyte ratio can better predict 30-day mortality in severe pneumonia patients.

June 6, 2026Frontiers in MedicineOpen Access

Improved prediction value of the CURB-65 score combined with the platelet-to-lymphocyte ratio for mortality in emergency department patients with severe community-acquired pneumonia

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This study evaluates if combining the CURB-65 score with the platelet-to-lymphocyte ratio can better predict 30-day mortality in severe pneumonia patients.
This retrospective study included 214 adults diagnosed with severe community-acquired pneumonia.
Multivariate logistic analysis was performed to identify independent mortality predictors and survival stratification was carried out using Kaplan–Meier analysis.
Receiver operating characteristic curve analysis compared the predictive performance of CURB-65 alone versus CURB-65 combined with PLR.
30-day all-cause mortality was observed at 25.7%.
CURB-65 score was determined as an independent predictor of mortality (OR 2.80, 95% CI 1.87–4.18).
The area under the curve for CURB-65 and PLR combined was superior at 0.772 (95% CI: 0.703–0.841), compared to CURB-65 alone at 0.702 (95% CI: 0.629–0.775).

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Implication

Retrospective study demonstrates improved 30-day mortality prediction in emergency patients with severe pneumonia, implying better risk assessment tools are needed.

Cite This Study

Lv et al. (2026) studied this question.

synapsesocial.com/papers/6a23b89f71a5da9775e74b2a https://doi.org/10.3389/fmed.2026.1836427

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Implication

Retrospective study demonstrates improved 30-day mortality prediction in emergency patients with severe pneumonia, implying better risk assessment tools are needed.

Improved prediction value of the CURB-65 score combined with the platelet-to-lymphocyte ratio for mortality in emergency department patients with severe community-acquired pneumonia

Key Points

Discussion

Implication

Cite This Study

Improved prediction value of the CURB-65 score combined with the platelet-to-lymphocyte ratio for mortality in emergency department patients with severe community-acquired pneumonia

Key Points

Discussion

Implication

Cite This Study

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