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June 6, 2026Frontiers in MedicineOpen Access

Case Report: Methylprednisolone-induced pheochromocytoma crisis resulting in cardiac arrest

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Authors

ZHZhenzhen HuWenzhou Central HospitalLHLianglei HouWenzhou Central HospitalAHAnwu HuangWenzhou Central Hospital

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Implication

Case report reveals cardiac arrest due to glucocorticoid-triggered pheochromocytoma crisis, indicating caution in treatment.

Key Points

  • To describe the clinical course of a patient who developed a pheochromocytoma crisis after receiving methylprednisolone.
  • A 38-year-old female patient was treated with methylprednisolone for urticaria and subsequently developed symptoms leading to cardiac arrest.
  • Management included extracorporeal membrane oxygenation and comprehensive pharmacological treatment, followed by further diagnostic investigations.
  • A computed tomography (CT) scan and biochemical tests confirmed the diagnosis of pheochromocytoma, leading to laparoscopic adrenalectomy.
  • The patient suffered cardiac arrest after glucocorticoid administration, with recurrent ventricular fibrillation observed on electrocardiogram.
  • CT imaging revealed an adrenal mass consistent with pheochromocytoma, confirmed by biochemical tests.
  • Following laparoscopic adrenalectomy, the patient showed significant clinical improvement.

Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/6a23b91b71a5da9775e751adhttps://doi.org/10.3389/fmed.2026.1779740
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