Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 6, 2026Journal of Drugs in Dermatology

Efficacy and Safety of Clascoterone Cream 1% and Clindamycin 1.2%/Benzoyl Peroxide 5% Gel Treatment in Patients With Acne

View Full Paper
Ask AI
Bookmark
Share

Authors

CKCharles KircikLKLeon KircikNSNicholas Squittieri

Discussion

Loading...

Member takes

Overview

Randomized trial assesses combination therapy for acne treatment in adolescents and adults, suggesting effective outcomes.

Key Points

  • This study aims to evaluate the efficacy and safety of clascoterone cream combined with clindamycin and benzoyl peroxide in treating acne vulgaris.
  • Open-label pilot study with patients aged ≥12 years
  • Combination therapy administered for 16 weeks
  • Outcomes assessed included IGA score, lesion counts, and DLQI scores.
  • At week 16, all patients achieved an IGA score of clear (0) or almost clear (1).
  • Significant reductions in inflammatory lesion counts (96.4%, P=0.007), noninflammatory counts (86.1%, P=0.009), and total lesion counts (92.0%, P=0.008).
  • Mean DLQI score reduction was 3.1 (P=0.014), indicating improved quality of life.

Cite This Study

Kircik et al. (2026) studied this question.

synapsesocial.com/papers/6a23b94671a5da9775e753f8https://doi.org/10.36849/jdd.9745
View Full Paper
Ask AI
Bookmark
Share