What question did this study set out to answer?

The aim is to present a rare case of a microduplication on chromosome 15q11.2 and its implications on development in the African context.

June 6, 2026BMC PediatricsOpen Access

A young girl with partial chromosome 15q11.2 microduplication: a case report in Cameroon

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Case report reveals growth and learning improvements in a girl with partial chromosome 15q11.2 microduplication, highlighting diagnostic needs.

The aim is to present a rare case of a microduplication on chromosome 15q11.2 and its implications on development in the African context.
Case report of a nine-year-old girl with growth and developmental issues.
Chromosomal microarray analysis was performed using Agilent 44 K array-CGH.
Parental testing confirmed that the microduplication was of maternal origin.
The girl was diagnosed with an interstitial 15q11.2 microduplication of 300.5 kb, classified as arr[GRCh37] 15q11.2(22784523_23085096)x3.
Nutritional support and levothyroxine treatment resulted in improved growth and school performance after three years of follow-up.
Initial differential diagnosis included Silver-Russell syndrome.

Betoko et al. (2026) studied this question.

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Case report reveals growth and learning improvements in a girl with partial chromosome 15q11.2 microduplication, highlighting diagnostic needs.