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This research aims to investigate how age and education affect attentional functions in patients with amyotrophic lateral sclerosis (ALS).

June 6, 2026Brain and BehaviorOpen Access

Attentional Function in Patients With Amyotrophic Lateral Sclerosis is Moderated by Age and Education

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Behavioral study examines attention in ALS patients, indicating cognitive screening importance for older individuals.

This research aims to investigate how age and education affect attentional functions in patients with amyotrophic lateral sclerosis (ALS).
Behavioral study utilizing the attention network test (ANT) in 27 ALS patients and 26 matched controls.
Focused on two attention components: alerting and executive functions, across different difficulty levels.
Assessed reaction times to examine cognitive processing, accounting for motor impairments in ALS patients.
Both ALS patients and controls exhibited intact executive and conflict effects based on relative reaction times.
Task accuracy for ALS patients was significantly lower than controls on incongruent hard targets (p<0.05).
Observed interaction effect between age and ALS pathology suggests increased cognitive vulnerability in older patients.

Zoubi et al. (2026) studied this question.

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