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June 6, 2026ToxinsOpen Access

Facial Paralysis Treatment and Facial Symmetrization with Botulinum Neurotoxin: A Narrative Review with Illustrative Clinical Cases

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Authors

MRMonica RengaRDRoberta D’EmilioGSGiovanni Salti

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Overview

Narrative review on botulinum neurotoxin injections improving facial symmetry in facial paralysis patients, suggesting clinical applications.

Key Points

  • This review aims to evaluate the efficacy of botulinum neurotoxin A for treating facial paralysis and improving symmetry. It also explores treatment strategies and outcomes.
  • Narrative review summarizing literature on botulinum neurotoxin A for facial paralysis treatment.
  • Illustrative clinical cases highlight practical applications of BoNT-A, including dosing strategies and treatment planning.
  • Discussion on use of functional scales and guided injections to enhance outcomes.
  • All three cases demonstrated clinically meaningful improvements in aesthetic and functional parameters post-treatment.
  • Patients exhibited reduced hyperkinesis and synkinesis after BoNT-A injections, showing enhanced facial symmetry.
  • Photographic evidence and functional grading scores were utilized to document improvements.

Cite This Study

Renga et al. (2026) studied this question.

synapsesocial.com/papers/6a23ba3c71a5da9775e75ee9https://doi.org/10.3390/toxins18060253
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Botulinum toxin type A in the treatment of synkinesis: a clinical case report and literature review2024 · 1 citations
  2. 2Reply: Facial Symmetry Enhancement and Brain Network Modifications in Facial Palsy Patients after Botulinum Toxin Type A Treatment2026
  3. 3373 The Use of Botulinum Toxin to Improve Cosmesis in Patients with Facial Asymmetry Following Facial palsy/synkinesis2024
  4. 4Botulinum toxin type A application on a toddler with peripheral facial palsy – case report2024
  5. 5Botulinum Toxin as a Functional Rehabilitation Tool: Integration between Aesthetics, Quality of Life, and Public Health2025