(133) Acceptability of Self-Sampling Human Papillomavirus Testing Among Transmasculine People

Introduction Cervical cancer remains a major global health concern, with Thailand reporting a high incidence rate of 16.4 per 100,000 person-years. Transmasculine (TM) individuals often encounter significant barriers to cervical cancer screening due to stigmatization, discrimination, and limited access to gender-affirming healthcare services. Despite the availability of human papillomavirus (HPV) testing as a primary screening tool, data on the feasibility and acceptability of self-sampling HPV testing among TM populations remain limited. Objective The primary objective of this study was to assess satisfaction and attitudes toward self-collected HPV testing among transmasculine individuals. The secondary objectives were to compare attitudes toward self-collected and provider-collected HPV testing methods, and between before and immendiately after self-collected method. Methods Each participant completed questionnaires about their attitudes toward collection methods both before and immediately after performing self-sampling for HPV using disposable kits, followed by provider-collected sampling. Demographic characteristics, cervical cancer screening knowledge, and satisfaction were assessed using structured questionnaires and analyzed with paired t-tests. Results A total of 220 TM individuals aged 25–65 years were recruited. Over 90% of participants reported very good to excellent experiences with the self-sampling method, with an overall satisfaction score of 4.4 out of 5. Participants rated higher satisfaction in the domains of privacy and collection instruments compared with the provider-collected method. The majority (63.1%) preferred self-sampling for future HPV testing. Notably, satisfaction scores significantly increased when comparing responses before and immediately after the self-sampling procedure. Knowledge assessment revealed gaps regarding the appropriate age to initiate screening, recommended screening intervals, and available testing methods. Conclusions Self-sampling HPV testing demonstrated high acceptability among transmasculine individuals and may enhance cervical cancer screening uptake. Targeted educational interventions are essential to address existing knowledge gaps and support broader implementation of inclusive screening programs. Disclosure No