Key result
Enterovirus encephalitis and meningitis outbreaks carry a ~13% attack rate and high hospitalization burden.
Why the study?
Enteroviruses are major causes of viral encephalitis and meningitis outbreaks, motivating an analysis of global outbreaks from 1960 to 2025 to map epidemiology, clinical manifestations, and serotypes.
Meta-Analysis (n=28,622)
Yes
Enterovirus encephalitis and meningitis outbreaks are a persistent global concern with high hospitalization rates (94.0%), primarily affecting children under 15 years old.
No takes yet. Share an insight, caveat, or question.
High hospitalization rates signal need for prompt pediatric evaluation in outbreaks; extends global epidemiology but leaves open targeted prevention strategies.
Zeng et al. (2026) conducted a meta-analysis in Enterovirus encephalitis and meningitis (n=28,622). Enterovirus outbreaks was evaluated on Overall attack rate (95% CI 6.1-22.3). Enterovirus encephalitis and meningitis outbreaks had an estimated overall attack rate of 13.2% (95% CI 6.1-22.3) and a pooled hospitalization rate of 94.0% (95% CI 85.9-99.2).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: