Evaluates two-stage testing's effectiveness in identifying Clostridioides difficile infections, indicating improved diagnosis within the veteran population.
Clostridioides difficile infection is a common community and nosocomial infection. Two-stage testing (initial polymerase chain reaction (PCR) test, followed by a confirmatory toxin test for PCR+ results) has been used to help differentiate colonization from infection. We report the impact of adopting two-stage testing at a tertiary Veterans Affairs medical center.
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Marker et al. (2026) studied this question.
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