Key result
Accelerated vascular ageing and arterial stiffness biomarkers predict adverse outcomes independently of brachial BP.
Why the study?
Clinical adoption of vascular ageing biomarkers has been constrained by fragmented markers, heterogeneous measurement, and absence of outcome-based decision pathways, leaving how they should be measured, interpreted, and translated into prevention an open question.
Vascular ageing biomarkers provide early prognostic signals for risk stratification, but clinical adoption requires harmonized measurement and outcome-anchored thresholds.
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May aid risk stratification independently of brachial BP; leaves open harmonized thresholds and prospective validation.
Liao et al. (2026) conducted a review in Accelerated vascular ageing. Accelerated vascular ageing was evaluated. Accelerated vascular ageing and arterial stiffness biomarkers consistently predict adverse outcomes independently of brachial blood pressure, though clinical adoption remains limited.
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