Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 6, 2026MedicinaOpen Access

Nutritional Status Is Associated with Bone Mineral Density, Vitamin D Levels, and Bone Turnover Markers in Patients with Proximal Femoral Fragility Fractures: A Retrospective Observational Study

View Full Paper
Ask AI
Bookmark
Share

Authors

MIMasahiro IinumaSt. Marianna University School of MedicineTHTakahiro HideshimaSt. Marianna University School of MedicineSMS. MachidaYokohama City Seibu Hospital

Discussion

Loading...

Member takes

Implication

Retrospective analysis demonstrates nutritional status influences bone health in older adults with fragility fractures, suggesting management implications.

Key Points

  • This study aims to assess the relationship between nutritional status and bone-related parameters in patients with proximal femoral fragility fractures.
  • Retrospective analysis of 108 patients undergoing surgery for proximal femoral fragility fractures.
  • Nutritional status evaluated using GNRI, PNI, and CONUT score.
  • Bone mineral density measured using dual-energy X-ray absorptiometry at the femoral neck and lumbar spine.
  • Significant positive correlation found between GNRI and PNI with femoral neck BMD (r = 0.48, r = 0.26; both p < 0.01).
  • CONUT score showed a negative correlation with femoral neck BMD (r = -0.27, p < 0.01).
  • Malnourished patients had lower femoral neck BMD and serum 25(OH)D with higher bone turnover markers compared to well-nourished patients.

Cite This Study

Iinuma et al. (2026) studied this question.

synapsesocial.com/papers/6a23baa771a5da9775e765b7https://doi.org/10.3390/medicina62061092
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Malnutrition in Older Hip Fracture Patients: Prevalence, Pathophysiology, Clinical Outcomes, and Treatment—A Systematic Review2025 · 29 citations
  2. 2Geriatric nutritional risk index as a predictor for fragility fracture risk in elderly with type 2 diabetes mellitus: A 9-year ambispective longitudinal cohort study2024 · 25 citations
  3. 3Association between malnutrition status and total joint arthroplasty periprosthetic joint infection and surgical site infection: a systematic review meta-analysis2024 · 29 citations
  4. 4Do nutritional assessment tools (PNI, CONUT, GNRI) predict adverse events after spinal surgeries? A systematic review and meta-analysis2024 · 26 citations
  5. 5Hospital Malnutrition: Prevalence, Identification and Impact on Patients and the Healthcare System2011 · 1,001 citations