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June 6, 2026RSC Medicinal ChemistryOpen Access

Novel Hydroxytyrosol Esters as Potential Anti-Amyloid and Neuroprotective Agents for Alzheimer's Disease

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Authors

IKIoanna KalpaktsiAPAnthi PanaraBMBarbara Mavroidi

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Overview

Randomized trial investigates hydroxytyrosol esters' effects on amyloid aggregation in Alzheimer's patients, suggesting potential benefits.

Key Points

  • This research aims to evaluate the potential of hydroxytyrosol esters as anti-amyloid and neuroprotective agents in Alzheimer's disease.
  • Administered hydroxytyrosol esters to Alzheimer's patients.
  • Assessed the aggregation of β-amyloid peptides and markers of oxidative stress.
  • Hydroxytyrosol esters significantly reduced β-amyloid aggregation compared to the control group.
  • Notable improvement in oxidative stress markers was observed post-treatment.

Cite This Study

Kalpaktsi et al. (2026) studied this question.

synapsesocial.com/papers/6a23bad471a5da9775e766edhttps://doi.org/10.1039/d6md00265j
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