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Protein structure analysis reveals insights into transmembrane CBASS effectors, suggesting further biochemical studies.
The protein was purified to homogeneity and crystallized, and its structure was determined at 1.6 Å resolution. The EfCap16 Nudix domain shares structural similarity with the Nudix superfamily and contains a conserved Nudix motif. This structure provides a reference framework for future biochemical and functional studies of transmembrane CBASS effectors.
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Makanyire et al. (2026) studied this question.
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