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June 6, 2026The Journal of Sexual Medicine

(432) The Value of Routine Testosterone and HbA1c Testing in Men Presenting with Erectile Dysfunction

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Authors

MFM FodeSWS B WangCJC Fuglesang S Jensen

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Overview

Randomized trial evaluates testosterone and HbA1c testing in men with erectile dysfunction, suggesting clinical importance.

Key Points

  • To assess the clinical utility of upfront testing for total testosterone and hemoglobin A1c in men with erectile dysfunction.
  • Retrospective analysis of medical records for men with organic erectile dysfunction from June 1, 2019, to June 1, 2024.
  • All participants underwent testing for total testosterone and HbA1c; those on ongoing testosterone treatment were excluded.
  • Descriptive and multivariable logistic regression analyses were conducted to identify predictors of hypogonadism and elevated HbA1c.
  • 26.8% of men had testosterone levels below 12 nmol/L, with obesity and comorbidity being significant predictors.
  • 23.7% of men had HbA1c levels above 48 mmol/mol; higher BMI and comorbidity index were associated with elevated HbA1c.
  • 7.4% of men without known diabetes had elevated HbA1c levels, indicating potential undiagnosed diabetes.

Cite This Study

Fode et al. (2026) studied this question.

synapsesocial.com/papers/6a23bbeb71a5da9775e774d5https://doi.org/10.1093/jsxmed/qdag118.382
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ASSESSING TESTOSTERONE LEVELS IN MEN WITH TYPE 2 DIABETES: A CROSS-SECTIONAL STUDY IN PRIMARY CARE2025
  2. 2895-P: Testosterone Replacement Therapy in Men with Hypogonadism and Type 2 Diabetes—ABCD Worldwide Audit2024
  3. 3Assessment of Hypogonadism and Erectile Dysfunction in Males with Prediabetes: A Cross-Sectional Study from North India2026
  4. 4(800) Beyond the IIEF Score: Biochemical and Hormonal Signatures Across Erectile Dysfunction Severity2026
  5. 52295-P: Erectile Dysfunction in Type 2 Diabetes: Prevalence and Risk Factors in a Real-World Clinical Cohort2026