Key result
Novel ablation strategies provide specialized deep-lesion techniques to eliminate refractory intramural VT.
Why the study?
Intramural ventricular tachycardia substrates reside deep within the myocardial wall beyond conventional energy delivery, requiring specialized techniques to balance transmural efficacy and safety.
Do advanced catheter ablation techniques improve transmural lesion formation and procedural success in patients with intramural ventricular tachycardia?
Do advanced catheter ablation techniques improve transmural lesion formation and procedural success in patients with intramural ventricular tachycardia?
Emerging advanced ablation techniques provide viable strategies to achieve critical lesion transmurality for deep intramural ventricular arrhythmias that are unreachable by standard radiofrequency delivery.
May aid refractory intramural VT ablation; leaves open need for prospective trials on safety and comparative efficacy.
Intramural ventricular tachycardia represents a formidable frontier in catheter ablation, where the arrhythmogenic substrate resides deep within the myocardial wall, often beyond the reach of conventional energy delivery. Achieving durable lesion formation in this setting requires a strategic balance between transmural efficacy and procedural safety. This review synthesizes the evolving landscape of intramural ventricular tachycardia ablation, detailing contemporary techniques, including bipolar ablation, needle-based approaches, simultaneous endocardial-epicardial delivery, and emerging energy modalities, each tailored to overcome the limitations of lesion depth and tissue heterogeneity. We examine diagnostic criteria, imaging adjuncts, and electroanatomic mapping strategies that guide procedural planning and highlight innovations aimed at enhancing lesion depth without compromising adjacent structures. By integrating current evidence and expert practice, this article offers a comprehensive framework for navigating the complexities of intramural ventricular tachycardia ablation and advancing outcomes in this challenging domain.
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Akrawinthawong et al. (2026) conducted a review in Intramural ventricular tachycardia. Advanced intramural ablation techniques (e.g., bipolar, simultaneous unipolar, PFA, ethanol, STAR) was evaluated. Emerging ablation strategies, including bipolar, simultaneous unipolar, pulsed-field, ethanol, and stereotactic radiotherapy, offer specialized methods to achieve deep lesion formation and eliminate refractory intramural ventricular tachycardia.
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