Retrospective Analysis of Acute Kidney Injury in  Hospitalizations with Covid-19.

INTRODUCTION: Coronavirus Disease 2019 (COVID-19) affected the entire world. While the effects on the lungs are more pronounced, the kidneys are also susceptible, and there is a potential risk of acute kidney injury (AKI) among COVID-19 patients. This study aimed to evaluate the incidence, clinical characteristics, and outcomes of AKI in patients hospitalized with COVID-19. METHODS: This study analyzed the incidence, characteristics, and outcomes of AKI in hospitalized patients with COVID-19. Medical records of 755 COVID-19 patients with AKI and 4647 patients without kidney injury admitted between March 2020 and July 2022 were analyzed at Karabuk Training and Research Hospital. We recorded patients' demographic information, length of stay, laboratory results, and the necessity for renal replacement therapy. AKI staging was based on initial and peak values of renal parameters such as serum. RESULTS: The results indicated a high incidence of AKI in COVID-19patients, particularly in those requiring intensive care units (ICU), where mortality rates were significantly high. The findings revealed that patients with AKI, especially those requiring hemodialysis (n = 110, 49.32%), had lower rates of recovery and discharge (n = 633, 83.84%), and significantly higher mortality rates compared to those without AKI (P = .032). The mortality rate in patients requiring hemodialysis was 33.64%, underscoring the severity of AKI and the high mortality risk associated with cases necessitating hemodialysis. CONCLUSION: The development of AKI in COVID-19 patients is associated with a significant increase in mortality risk, indicating the need for further detailed investigations to better understand this condition.