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June 6, 2026Annals of Movement DisordersOpen Access

Implantation order and pneumocephalus independently predict radial electrode deviation in bilateral subthalamic nucleus deep brain stimulation: A single-surgeon analysis

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Authors

VVV. VemulaAPAnil Kumar Reddy PapasaniCKChandra Sekhar Reddy Kalakoti

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Overview

Retrospective analysis examines how implantation order and pneumocephalus affect electrode placement accuracy in Parkinson’s disease.

Key Points

  • This study investigates how implantation order and pneumocephalus impact radial deviation of electrodes in STN DBS for Parkinson's disease.
  • Retrospective, single-surgeon analysis of 45 patients (90 electrodes) undergoing bilateral STN DBS.
  • Actual lead positions assessed via fusion of preoperative MRI and postoperative CT scans.
  • Univariate and multivariate linear regression analyses conducted to evaluate associations.
  • Mean radial deviation was 2.18 ± 0.52 mm, with second-implanted electrodes deviating more (2.46 ± 0.55 mm) than first-implanted electrodes (1.89 ± 0.41 mm; P < 0.001).
  • Mean pneumocephalus volume was 11.6 ± 6.9 cm³ and significantly correlated with radial deviation (r = 0.48, P = 0.001).
  • Both pneumocephalus volume (β = 0.031 mm/cm³; P = 0.001) and implantation order (β = 0.49 mm; P < 0.001) independently predicted deviation.

Cite This Study

Vemula et al. (2026) studied this question.

synapsesocial.com/papers/6a23bc0571a5da9775e776f5https://doi.org/10.4103/aomd.aomd_14_26
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