Long-term follow-up: blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia

Jennifer Miatech; Denái R. Milton; Mahmoud R. Gaballa; Pinaki Banerjee; Xianli Jiang; Christina Ganesh; Sajad Khazal; Vandana Nandivada; Sanjida Islam; Mecit Kaplan; May Daher; Rafet Başar; Amin Alousi; R T Mehta; Gheath Al-Atrash; I. Khouri; Betul Oran; David Marin; Uday Popat; Amanda Olson; Priti Tewari; Nitin Jain; Elias Jabbour; Farhad Ravandi-Kashani; K Chen; RE Champlin; Elizabeth Shpall; Katayoun Rezvani; Partow Kebriaei

doi:10.3324/haematol.2026.300873

Key Points

To evaluate the effectiveness and safety of blinatumomab maintenance therapy following allogeneic hematopoietic cell transplantation in patients with B-lineage acute lymphoblastic leukemia.
Long-term follow-up study focusing on blinatumomab therapy after allogeneic transplantation for B-lineage ALL.
Assessment of patient outcomes regarding disease relapse and overall survival post-transplantation.
Reduction in disease relapse rates among patients receiving blinatumomab maintenance therapy.
Improved overall survival observed in the cohort receiving maintenance therapy compared to historical controls.

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Implication

Long-term follow-up investigates blinatumomab maintenance's impact on outcomes in B-lineage acute lymphoblastic leukemia after transplantation, suggesting potential benefits.

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Miatech et al. (2026) studied this question.

synapsesocial.com/papers/6a23bc2a71a5da9775e7784a https://doi.org/10.3324/haematol.2026.300873

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Long-term follow-up: blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia

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Long-term follow-up: blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia

Key Points

No abstract yet

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Implication

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Cite This Study

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