(104) Risk Factors for Sexual Inactivity and Sexual Dysfunction in Women with Pelvic Floor Disorders

Introduction Sexual health is frequently impaired among women with pelvic floor disorders (PFD); however, risk factors for sexual inactivity and sexual dysfunction are uncertain. Objective To analyze influencing factors in sexual activity and function of women with PFD. Methods A cross-sectional study about sexual health among women attended in an urogynaecology unit of a tertiary university hospital to manage: anal incontinence (AI), urinary incontinence (UI) and/or prolapse (POP). A condition-specific Spanish validated questionnaire was used to assess sexual activity and sexual function (PISQ-IR). Demographical data, 3 Spanish validated questionnaires (B-SAQ, ICIQ and PFDI-20), POPQ stage and modified Oxford scale were also collected. Results Among 1169 analyzed women, 71.3% were menopausal, mean (SD) age was 60.2 (13.5) years. Up to 88.1% of women reported UI, 40.6% symptomatic POP and 54.4% AI. In the multivariate analysis, we found biological risk factors for sexual inactivity (age: aOR=0.93; 95% CI 0.91-0.94; p<0.001; symptomatic POP: aOR=0.67; 95% CI 0.48-0.94; p=0.020 and hypertension: aOR=0.54%; 95% CI 0.38-0.78; p=0.001) and sexual dysfunction (symptomatic POP: β (beta)=-0.138; 95% CI -0.223; -0.053; p=0.002; AI symptoms: β (beta)=-0.094; 95% CI -0.177; -0.011; p=0.027 and dyspareunia: β (beta)=-0.289; 95% CI -0.373; -0.206; p<0.001), psychological factors associated to sexual dysfunction (mental health problems: β (beta)=-0.142; 95% CI -0.256; -0.027; p=0.015), a social influencing factor for being SA (stable relationship aOR=4.84; 95% CI 3.47-6.74; p<0.001) and biological risk factors for better sexual function (higher Oxford: aOR= 0.82; 95% CI 0.69-0.98; p=0.029 and younger age: aOR=0.96; CI 95% 0.93-0.98; p=0.002). The rate of NSA women was 40.4%. The ratio of women with sexual dysfunction was 24.4%.The main reason for sexual inactivity was lack of interest (74.8%), while urogynecological pathology were the cause of inactivity in a much smaller proportion (24.1%). Usual sexual activity frequency was restricted due to fear of leaking urine/stool and/or POP by 48.6% of SA women.Less than a half of SA women stated that they were satisfied with their sexual life (45.8%). Clinical implications: The most important risk factor for sexual inactivity was the absence of having a partner, while dyspareunia influencing the most for sexual dysfunction. Strengths & Limitations: Strengths include the use of PISQ-IR and other validated questionnaires and the multivariate analysis. As a limitation, the cross-sectional design and that is a single-centre study based on complex PFD female population, so generalization of results should be made with caution. Conclusions Several biopsychosocial factors influence sexual activity and function in women with PFD (age, symptomatic POP, hypertension, AI symptoms, dyspareunia, mental health problems, Oxford score, stable relationship). Moreover, PFD is the reason for sexual inactivity or decreased sexual activity frequency among one out of four NSA women and one out of two SA, respectively. A quarter of women with PFD are at risk of female sexual dysfunction. Therefore, satisfaction with sexual life could be affected. PISQ-IR allows health care professionals to understand the impact of inactivity or sexual symptoms in overall satisfactory sexual life due to PFD. Disclosure No