Key result
Endothelins play a significant pathophysiologic role in cardiovascular diseases, highlighting endothelin antagonists and converting enzyme inhibitors as potential therapeutic targets.
Design
Review
Authors
Loading...
Endothelin pathway targeting warrants trial evaluation in hypertension and heart failure; leaves open clinical adoption without randomized confirmation.
Endothelins play a broad pathophysiologic role in cardiovascular diseases, suggesting endothelin antagonists and converting enzyme inhibitors as potential therapeutic targets.
Schiffrin et al. (1997) conducted a review in Cardiovascular disease. Endothelin was evaluated. Endothelins play a significant pathophysiologic role in cardiovascular diseases, highlighting endothelin antagonists and converting enzyme inhibitors as potential therapeutic targets.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: