Why the study?
Does in-vehicle exposure to traffic air pollutants alter heart rate variability in volunteers with type 2 diabetes?
Does in-vehicle exposure to traffic air pollutants alter heart rate variability in volunteers with type 2 diabetes?
In-vehicle exposure to traffic air pollutants acutely reduces heart rate variability in patients with type 2 diabetes.
Answers are grounded in this paper and cite their sources.
Traffic pollutant exposure may acutely alter HRV in type 2 diabetes; leaves open causal cardiovascular risk and need for confirmatory trials.
OBJECTIVE: To pilot a protocol to evaluate acute cardiovascular effects in in-vehicle exposure to traffic air pollutants in people with diabetes. METHODS: Twenty-one volunteers with type 2 diabetes were passengers on 90- to 110-minute car rides on a busy highway. We measured in-vehicle particle number and mass (PM2.5) nitrogen dioxide, and carbon monoxide and heart rate, heart rate variability (HRV), and blood pressure. RESULTS: Compared with pre-ride measurements, we found a decrease in high frequency (HF) HRV from pre-ride to next day (ratio 0.66, 95% CI = 0.47 to 0.93) and an increase in low frequency to HF ratio at post-ride (ratio 1.92, 95% CI = 1.21 to 3.05) at post-ride. Interquartile range increases in measured pollutants were associated with next-day decreases in HR HRV. CONCLUSIONS: This protocol appears useful for assessing acute adverse cardiovascular effects of in-vehicle exposures among people who have diabetes.
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Laumbach et al. (2010) studied this question.
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