Key result
BNP and NT-proBNP levels are elevated in various critical illnesses and pulmonary diseases, serving as potential markers of severity and prognosis beyond heart failure.
Why the study?
What is the clinical utility of BNP and NT-proBNP in critical illness and pulmonary diseases?
Population
Patients with critical illness and pulmonary diseases
Design
Review
Authors
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Caution advised interpreting BNP/NT-proBNP elevations in non-HF critical illness; leaves open their prognostic utility pending prospective validation.
What is the clinical utility of BNP and NT-proBNP in critical illness and pulmonary diseases?
BNP and NT-proBNP are not specific to heart failure and can be elevated in various critical illnesses and pulmonary diseases, where they may indicate disease severity and prognosis.
Phua et al. (2005) conducted a review in Critical illness and pulmonary diseases. B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) was evaluated on Utility as biomarkers of severity and prognosis. BNP and NT-proBNP levels are elevated in various critical illnesses and pulmonary diseases, serving as potential markers of severity and prognosis beyond heart failure.
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