Key result
Obesity in young women was associated with a blunted sympathetic response and a significantly lower increase in energy expenditure after mixed-food ingestion compared to non-obese controls (6.7% vs 11.2%, p<0.05).
Why the study?
Does mixed-food ingestion alter sympathovagal activities and energy expenditure differently in obese compared to non-obese young women?
Population
16 age- and height-matched obese and non-obese young women
Comparison
Mixed-food ingestion (480 kcal) vs Resting condition (preprandial)
Design
Cross-sectional
Authors
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May support impaired thermogenesis in obesity maintenance; hypothesis-generating and should not change practice without longitudinal data.
Observational (n=16)
Does mixed-food ingestion alter sympathovagal activities and energy expenditure differently in obese compared to non-obese young women?
Absolute Event Rate: 6.7% vs 11.2%
p-value: p=<0.05
Obese young women exhibit a blunted sympathetic and thermogenic response to food intake compared to non-obese controls, suggesting a potential mechanism for obesity maintenance.
Matsumoto et al. (2001) conducted an observational in Obesity (n=16). Obesity vs. Non-obese controls was evaluated on Magnitude of energy expenditure increase above preprandial resting condition after mixed-food ingestion (p=<0.05). Obesity in young women was associated with a blunted sympathetic response and a significantly lower increase in energy expenditure after mixed-food ingestion compared to non-obese controls (6.7% vs 11.2%, p<0.05).
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