Key result
Coronary artery disease severity measured by CCTA independently predicted all-cause mortality (HR 1.58; 95% CI 1.42-1.76) and provided incremental prognostic value over LVEF and clinical variables.
Why the study?
Does CCTA-derived CAD severity and LVEF predict all-cause mortality in patients with suspected obstructive CAD?
Cohort (n=13,966)
Yes
Does CCTA-derived CAD severity and LVEF predict all-cause mortality in patients with suspected obstructive CAD?
Hazard Ratio: 1.58 (95% CI 1.42–1.76)
CCTA-derived CAD severity provides incremental prognostic value for predicting all-cause mortality over routine clinical predictors and LVEF in patients with suspected obstructive CAD.
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CCTA CAD severity may refine mortality risk stratification beyond LVEF; leaves open prospective validation before routine adoption.
Chow et al. (2011) conducted a cohort in Coronary artery disease (n=13,966). Coronary artery disease severity and LVEF <50% measured by CCTA vs. Normal or nonobstructive CAD and LVEF ≥50% was evaluated on All-cause mortality (HR 1.58, 95% CI 1.42 to 1.76). Coronary artery disease severity measured by CCTA independently predicted all-cause mortality (HR 1.58; 95% CI 1.42-1.76) and provided incremental prognostic value over LVEF and clinical variables.
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