Sympathectomy Effects on Intra-Abdominal Organ Catecholamine Levels in a Streptozotocin-Induced Diabetic Rat Model

Figures

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  Figure 1. Body weight (A), food consumption (B), and water intake (C) in the control group and the groups treated with GNT, STZ, and a combination of GNT−STZ (n = 6). The represented values are the mean (± SEM), * p < 0.05 vs. the control group.

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  Figure 2. NE concentrations (ng/g) in different intra-abdominal tissues, including the paraganglia, liver, portal vein, pancreas, duodenum, and heart of control animals, the sympathectomized group (GNT), the group administered with STZ, and the group administered with the combination of GNT–STZ. The data are the mean ± SEM (n = 6), a p < 0.05 compared with the control group, c p < 0.05 compared with the STZ group, and d p < 0.05 compared with the GNT–STZ group.

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  Figure 3. Effect of the administration of GNT and STZ on E concentrations (ng/g) in the liver, pancreas, and heart. Values are expressed as the mean ± SEM in each experimental group (n = 6), a p < 0.05 compared with the control group, c p < 0.05 compared with the STZ group, and d p < 0.05 compared with the GNT–STZ group.

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  Figure 4. DA concentrations (ng/g) in different tissues of male Wistar rats, including the paraganglia, liver, pancreas, duodenum, and heart of control animals, the sympathectomized group (GNT), the group administered with STZ, and the group administered with the combination of GNT–STZ. The data are the mean ± SEM, (n = 6), a p < 0.05 compared with the control group.

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  Figure 5. DA, NE, and E concentrations (μg/gland) in the adrenal medulla of the control group, sympathectomized (GNT) group, diabetic (STZ) group, and the interaction of sympathectomy and diabetes (GNT–STZ) group, male rats (n = 6 for each group). Values are the mean ± SEM. a p < 0.05 compared with the control group.