Key result
Interaction of duck gizzard tropomyosin heterodimers with F-actin caused a 2-6 degrees C shift in the tropomyosin thermal transition to a higher temperature.
Differential scanning calorimetry demonstrates that the interaction of tropomyosin heterodimers with F-actin stabilizes tropomyosin, shifting its thermal unfolding to higher temperatures.
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Stabilizes tropomyosin in avian smooth muscle models; leaves open relevance to cardiac sarcomere function or disease.
Levitsky et al. (2000) studied this question. Tropomyosin vs. Free tropomyosin or F-actin alone was evaluated on Thermal transition shift. Interaction of duck gizzard tropomyosin heterodimers with F-actin caused a 2-6 degrees C shift in the tropomyosin thermal transition to a higher temperature.
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