Key result
Obese diabetics with autonomic neuropathy had a significantly higher apnea-hypopnea index compared to those without neuropathy (39.5 vs 15.8, p<0.01).
Why the study?
Does the presence of diabetic autonomic neuropathy increase the risk and severity of obstructive sleep apnea-hypopnea in obese diabetics?
Cross-Sectional (n=28)
Does the presence of diabetic autonomic neuropathy increase the risk and severity of obstructive sleep apnea-hypopnea in obese diabetics?
Absolute Event Rate: 39.5% vs 15.8%
p-value: p=<0.01
The presence of diabetic autonomic neuropathy in obese diabetic patients is associated with a significantly higher frequency and severity of obstructive sleep apnea-hypopnea.
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Associated OSAH severity in obese diabetics with DAN warrants evaluation; leaves open causality and needs prospective confirmation before practice change.
Bottini et al. (2007) conducted a cross-sectional in Obstructive sleep apnea in obese diabetics (n=28). Diabetic autonomic neuropathy vs. Obese diabetics without autonomic neuropathy and obese controls was evaluated on Apnea-hypopnea index (AHI) (p=<0.01). Obese diabetics with autonomic neuropathy had a significantly higher apnea-hypopnea index compared to those without neuropathy (39.5 vs 15.8, p<0.01).
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