Why the study?
Does lidocaine prophylaxis reduce the incidence of primary ventricular fibrillation in patients with acute myocardial infarction?
Does lidocaine prophylaxis reduce the incidence of primary ventricular fibrillation in patients with acute myocardial infarction?
The declining baseline incidence of primary ventricular fibrillation in acute myocardial infarction makes routine prophylactic lidocaine use unfavorable due to a high number needed to treat and potential excess mortality.
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Renders routine lidocaine prophylaxis unfavorable in AMI; confirms temporal decline in primary VF incidence.
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Antman et al. (1992) studied this question.
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