Key result
Post-RFCA IV corticosteroids linked to ~82% lower odds of early AF recurrence.
Why the study?
Does intravenous corticosteroid use prevent early recurrence of atrial fibrillation immediately following radiofrequency catheter ablation?
Case-Control (n=68)
No
Does intravenous corticosteroid use prevent early recurrence of atrial fibrillation immediately following radiofrequency catheter ablation?
Odds Ratio: 0.18 (95% CI 0.04–0.78)
Absolute Event Rate: 13.5% vs 35.5%
p-value: p=0.02
Intravenous corticosteroids administered immediately post-ablation may safely and significantly reduce the risk of early in-hospital atrial fibrillation recurrence.
Should not yet change routine post-ablation care; leaves open whether prophylactic corticosteroids offer.
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Sood et al. (2011) conducted a case-control in Atrial Fibrillation (n=68). Intravenous corticosteroids vs. No intravenous corticosteroids was evaluated on Early recurrence of atrial fibrillation (ERAF) defined as any AF >10 minutes during hospitalization (Adjusted OR 0.18, 95% CI 0.04-0.78, p=0.02). Administration of intravenous corticosteroids immediately following RFCA was associated with an 82% reduction in the odds of early recurrence of atrial fibrillation (adjusted OR 0.18, 95% CI 0.04-0.78, p=0.02).
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