Key result
Contrast-induced nephropathy affects ~19% of primary PCI patients and is linked to significantly higher mortality.
Why the study?
Patients undergoing primary PCI for AMI may be at higher risk of contrast-induced nephropathy due to hemodynamic instability and the unfeasibility of adequate prophylaxis.
What are the incidence, predictors, and outcomes of contrast-induced nephropathy in patients undergoing primary PCI for acute myocardial infarction?
Observational (n=208)
What are the incidence, predictors, and outcomes of contrast-induced nephropathy in patients undergoing primary PCI for acute myocardial infarction?
Contrast-induced nephropathy frequently complicates primary PCI for AMI, is associated with higher mortality, and is predicted by older age, longer time-to-reperfusion, higher contrast volume, and IABP use.
No takes yet. Share an insight, caveat, or question.
CIN identification may aid risk stratification in primary PCI; leaves open whether targeted prevention reduces associated mortality.
Marenzi et al. (2004) conducted an observational in Acute myocardial infarction (n=208). Primary percutaneous coronary intervention was evaluated on Contrast-induced nephropathy (rise in serum creatinine >0.5 mg/dl). Contrast-induced nephropathy occurred in 19% of patients undergoing primary PCI for AMI and was associated with significantly higher mortality compared to those without CIN (31% vs. 0.6%; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: