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January 13, 1983New England Journal of Medicine

Noninvasive Tests in the Initial Evaluation of Heart Murmurs in Children

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Why the study?

Do noninvasive tests (ECG, chest radiography, M-mode echocardiography) change the clinical diagnosis in children referred for evaluation of a heart murmur?

Population

280 children older than one month, newly referred for evaluation of a heart murmur.

Comparison

Noninvasive tests following history and physical… vs Clinical evaluation alone

Design

Cohort

Authors

Jane W. NewburgerJane W. NewburgerPediatric CardiologyARAmnon RosenthalPediatric / Congenital CardiologyRWRoberta G. WilliamsPediatric / Congenital Cardiology

Discussion

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Implication

Supports deferring routine noninvasive tests after expert evaluation; leaves open generalizability beyond single-center cohorts.

Structured PICO

Do noninvasive tests (ECG, chest radiography, M-mode echocardiography) change the clinical diagnosis in children referred for evaluation of a heart murmur?

P
Population
280 children older than one month, newly referred for evaluation of a heart murmur.
I
Intervention
Noninvasive tests (electrocardiography, chest radiography, and M-mode echocardiography) following history and physical examination
C
Comparator
Clinical evaluation alone (history and physical examination)
O
Outcome
Change in clinical diagnosis (presence vs absence of heart disease) after reviewing diagnostic tests

Routine noninvasive testing (ECG, chest radiography, echocardiography) is unlikely to change the clinical diagnosis made by a qualified pediatric cardiologist in children referred for a heart murmur.

Cite This Study

Newburger et al. (1983) studied this question.

synapsesocial.com/papers/6a24672f2a275e90cb65b093https://doi.org/10.1056/nejm198301133080201

Topics

EchocardiographyCardiomyopathy
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ATTITUDINAL FACTORS IN CONGENITAL HEART DISEASE1966 · 82 citations
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  4. 4The Morbidity of Cardiac Nondisease in Schoolchildren1967 · 246 citations
  5. 5Physical Activities and Rheumatic Heart Disease in Asymptomatic Patients1962 · 14 citations