Key result
The time-domain lossy tube-load model outperformed the lossless model in representing central aortic versus peripheral blood pressure waves, with an RMSE of 3.1 mm Hg versus 3.5 mm Hg (p<0.05).
Why the study?
Does a time-domain lossy tube-load model improve the accuracy of modeling central aortic and peripheral blood pressure waves compared to a lossless model in cardiac surgery patients?
Does a time-domain lossy tube-load model improve the accuracy of modeling central aortic and peripheral blood pressure waves compared to a lossless model in cardiac surgery patients?
A data-driven lossy tube-load model more accurately represents the relationship between central and peripheral blood pressure waves than a lossless model.
Answers are grounded in this paper and cite their sources.
May modestly improve central-peripheral BP wave representation in cardiac surgery; extends tube-load modeling but leaves open clinical utility.
In this paper, we present and validate a data-driven method to lossy tube-load modeling of arterial tree in humans. In the proposed method, the lossy tube-load model is fitted to central aortic and peripheral blood pressure (BP) waves in the time domain. For this purpose, we employ a time-domain lossy tube-load model in which the wave propagation constant is formulated to two terms: one responsible for the alteration of wave amplitude and the other for the transport delay. Using the experimental BP data collected from 17 cardiac surgery patients, we showed that the time-domain lossy tube-load model is able to accurately represent the relation between central aortic versus upper-limb and lower-limb BP waves. In addition, the comparison of lossy versus lossless tube-load models revealed that (1) the former outperformed the latter in general with the root-mean-squared errors (RMSE) of 3.1 mm Hg versus 3.5 mm Hg, respectively (p-value < 0.05), and (2) the efficacy of the former over the latter was more clearly observed in case the normalized difference in the mean central aortic versus peripheral BP was large; when the difference was >5% of the underlying mean BP, lossy and lossless models showed the RMSE of 2.7 mm Hg and 3.7 mm Hg, respectively (p-value < 0.05).
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Abdollahzade et al. (2014) studied Cardiac surgery (n=17). Time-domain lossy tube-load model vs. Lossless tube-load model was evaluated on Root-mean-squared errors (RMSE) of central aortic versus peripheral BP waves (p=< 0.05). The time-domain lossy tube-load model outperformed the lossless model in representing central aortic versus peripheral blood pressure waves, with an RMSE of 3.1 mm Hg versus 3.5 mm Hg (p<0.05).
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