Key result
In dogs with myxomatous mitral valve disease, maximal left atrial volume (LAVmax) was a significant independent predictor of cardiac death (HR 2.32; 95% CI 1.10-4.89; P=0.024).
Why the study?
Does echocardiographic assessment of left atrial morphology and function predict cardiac-related death in dogs with myxomatous mitral valve disease?
Cohort (n=115)
Does echocardiographic assessment of left atrial morphology and function predict cardiac-related death in dogs with myxomatous mitral valve disease?
Hazard Ratio: 2.32 (95% CI 1.1–4.89)
p-value: p=0.024
Left atrial maximal volume and mitral valve E wave velocity are strong independent predictors of cardiac death in dogs with myxomatous mitral valve disease.
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LAVmax may refine cardiac death risk stratification in MMVD; leaves open validation and incremental value in prospective studies.
Toaldo et al. (2018) conducted a cohort in Myxomatous mitral valve disease (MMVD) (n=115). Maximal left atrial volume (LAVmax > 3.53 mL/kg) was evaluated on Cardiac-related death (HR 2.32, 95% CI 1.10-4.89, p=0.024). In dogs with myxomatous mitral valve disease, maximal left atrial volume (LAVmax) was a significant independent predictor of cardiac death (HR 2.32; 95% CI 1.10-4.89; P=0.024).
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