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). Moreover, the BMP-2-loaded scaffolds display a biphasic release behavior, characterized by an initial burst release up to 168 h followed by a slower, sustained release from 168 to 456 h. Overall, these results demonstrate that radially graded porous Fe-35Mn scaffolds combine favorable mechanical compatibility, tunable biodegradation, and sustained growth factor delivery, highlighting their potential as biodegradable load-bearing scaffolds for bone regeneration.
Chen et al. (Fri,) studied this question.