Key result
Cyanotic and left heart obstructive repairs are linked to ~16-fold higher late sudden death risk.
Why the study?
What is the long-term risk of sudden cardiac death in pediatric patients surviving surgical repair of common congenital heart defects?
Cohort (n=3,589)
What is the long-term risk of sudden cardiac death in pediatric patients surviving surgical repair of common congenital heart defects?
p-value: p=< 0.01
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Patients surviving surgery for cyanotic or left heart obstructive congenital heart defects face a significantly increased, time-dependent risk of late sudden death, particularly after the second postoperative decade.
Silka et al. (1998) conducted a cohort in Common congenital heart defects (n=3,589). Cyanotic or left heart obstructive lesions (aortic stenosis, coarctation, transposition of the great arteries, tetralogy of Fallot) vs. Other common congenital heart defects was evaluated on Late sudden death (p=< 0.01). Patients surviving operation for cyanotic or left heart obstructive lesions had a higher rate of late sudden death than those with other defects (1/454 vs 1/7,154 patient-years; p<0.01).
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