Risk factors for residual cancer and lymph node metastasis after non-curative endoscopic resection of colorectal cancer: a multicenter retrospective study

Soo Young Oh; Hyung-Hoon Oh; Young  Cheol Kim; Dong-Hyun Kim; Young-Eun Joo; Hyun-Soo Kim; Won-Kyung Kang; Jong Lyul Lee; Yong Sik Yoon; Chan Wook Kim; In Ja Park; Seok-Byung Lim

doi:10.1186/s12876-026-04988-y

June 5, 2026BMC GastroenterologyOpen Access

Risk factors for residual cancer and lymph node metastasis after non-curative endoscopic resection of colorectal cancer: a multicenter retrospective study

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Key Points

Determine the incidence of residual cancer and lymph node metastasis (LNM) and identify risk factors after non-curative endoscopic resection of colorectal cancer.
Multicenter retrospective study conducted across four hospitals from 2015 to 2020.
Included patients who underwent radical surgery after non-curative endoscopic resection of T1 colorectal cancer.
Defined non-curative resection by features like positive margins and deep submucosal invasion.
Residual cancer found in 3.7% of patients and lymph node metastasis found in 7.7%.
Independent predictors for residual cancer included ESD procedure (OR 9.87, P < 0.001) and positive margin features.
For LNM, key risk factors were submucosal invasion depth ≥ 1000 μm (OR 4.66, P = 0.015) and poor differentiation (OR 4.30, P = 0.026).

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Implication

Multicenter retrospective study identifies risk factors for residual cancer and lymph node metastasis after non-curative endoscopic resection in colorectal cancer.

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Cite This Study

Oh et al. (2026) studied this question.

synapsesocial.com/papers/6a250a3c7def13d035e1a6db https://doi.org/10.1186/s12876-026-04988-y

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Risk factors for residual cancer and lymph node metastasis after non-curative endoscopic resection of colorectal cancer: a multicenter retrospective study

Key Points

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Implication

Discussion

Cite This Study

Risk factors for residual cancer and lymph node metastasis after non-curative endoscopic resection of colorectal cancer: a multicenter retrospective study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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