What question did this study set out to answer?

This research aims to estimate the annual prevalence of diabetic ketoacidosis (DKA) and severe hypoglycemia (SH) among individuals with type 2 diabetes (T2D).

June 7, 2026Diabetes

2978-LB: Annual Prevalence of Diabetic Ketoacidosis and Severe Hypoglycemia in Type 2 Diabetes

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This research aims to estimate the annual prevalence of diabetic ketoacidosis (DKA) and severe hypoglycemia (SH) among individuals with type 2 diabetes (T2D).
Analyzed Inovalon Insights claims data from 2017-2024 for Commercial, Managed Medicaid, and Medicare Advantage plans.
Counted emergency department (ED) visits with subsequent inpatient (IP) admissions as IP episodes.
Defined prevalence as the proportion of individuals with T2D experiencing ≥1 event in a calendar year, using ICD 10 codes.
DKA prevalence increased from 18 to 32 per 10,000 overall; pediatric DKA increased from 13 to 36, adult DKA from 18 to 32.
SH prevalence remained stable overall (0.61 to 0.55 per 10,000) and in adults (0.63 to 0.55 per 10,000), but increased in pediatrics from 0.10 to 0.60 per 10,000.
Most events were managed inpatient: DKA (peds 94%, adults 98%) and SH (peds 58%, adults 90%).

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Implication

Randomized trial estimates annual prevalence of DKA and SH in individuals with type 2 diabetes, indicating rising DKA rates, especially in youth.

Cite This Study

WYSHAM et al. (2026) studied this question.

synapsesocial.com/papers/6a250ac07def13d035e1ac41 https://doi.org/10.2337/db26-2978-lb

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Implication

Randomized trial estimates annual prevalence of DKA and SH in individuals with type 2 diabetes, indicating rising DKA rates, especially in youth.

2978-LB: Annual Prevalence of Diabetic Ketoacidosis and Severe Hypoglycemia in Type 2 Diabetes

Key Points

Discussion

Implication

Cite This Study

2978-LB: Annual Prevalence of Diabetic Ketoacidosis and Severe Hypoglycemia in Type 2 Diabetes

Key Points

Discussion

Implication

Cite This Study

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