1610-P: Culturally Tailored mHealth-Based Diabetes Prevention Program Shows Promise for Weight Loss in a Population with Low Income at Risk for Type 2 Diabetes

Introduction and Objective: To evaluate the efficacy of a culturally tailored mHealth-based Diabetes Prevention Program (DPP) with fresh produce on weight loss among Chinese Americans with low income at risk for type 2 diabetes (T2D). Methods: In this 6-month randomized controlled trial, 150 Chinese Americans at risk for T2D were randomized to the intervention or control (75/group). The intervention included 2-3 DPP brief videos per week for 12 weeks, biweekly supportive calls with community health workers for 12 weeks, and weekly fresh produce for 10 weeks. Weight was measured at baseline, 3, and 6 months. Results: Most participants (mean age: 50.0±12.6 years, 83% female, mean BMI: 27.2) had limited English proficiency (88%) and an annual household income below USD $55,000 (70%). Engagement was high: 72.0% completed DPP videos and 83.8% completed calls. Retention at 6 months was 97.3%. Overall program satisfaction was high (9.1/10). Baseline weight did not differ between groups (intervention: 155.3 lbs vs. control: 154.6 lbs). Both groups had significant weight loss at 3 and 6 months, with a trend toward greater loss in the intervention group, though between-group differences were not statistically significant (Table 1). Conclusion: This culturally tailored mHealth-based DPP with fresh produce was feasible and acceptable among low-income adults at risk for T2D. Larger studies may be needed to identify subgroups most likely to benefit. Disclosure J. Liu: None. X. Yang: None. C. Teng: None. Y. Zhao: None. H. Li: None. S. Yi: None. J.M. Beasley: None. L. Hu: None. Funding American Diabetes Association (11-22-ICTSN-08)