Safety, treatment adherence, and patient satisfaction in major ozone autohemotherapy: a single-center retrospective study

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Major ozone autohemotherapy has a 65% treatment completion rate, with procedural adverse events—primarily difficult venous access, which is more common in older patients—significantly increasing the risk of treatment non-completion. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Ekrem Yılmaz; Cemal Çevik

doi:10.32322/jhsm.1905576

May 19, 2026Journal of Health Sciences and MedicineOpen Access

Safety, treatment adherence, and patient satisfaction in major ozone autohemotherapy: a single-center retrospective study

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Key Points

The aim was to evaluate adverse events, treatment adherence, and patient satisfaction during major ozone autohemotherapy.
Single-center retrospective study involving 240 patients aged ≥18 years undergoing major ozone autohemotherapy from January 2024 to November 2025.
Patients received approximately 100 ml of venous blood with ozone concentrations ranging from 15 to 35 µg/ml, scheduled twice weekly.
Data was collected on adverse events, treatment completion, and factors related to venous access.
Mean age of participants was 53.1 years, with a completion rate of 65.0% for planned sessions.
Adverse events occurred in 11.3% of patients, primarily related to venous access, with 7.1% experiencing difficult venous access.
Age ≥60 years had higher odds of difficult venous access (OR=3.79; 95% CI 1.38-10.41).

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Implication

Retrospective study evaluates adverse events and patient satisfaction during ozone autohemotherapy, indicating implications for treatment adherence.

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Yılmaz et al. (2026) studied this question.

synapsesocial.com/papers/6a250b4c7def13d035e1b442 https://doi.org/10.32322/jhsm.1905576

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Safety, treatment adherence, and patient satisfaction in major ozone autohemotherapy: a single-center retrospective study

Key Points

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Cite This Study

Safety, treatment adherence, and patient satisfaction in major ozone autohemotherapy: a single-center retrospective study

Key Points

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Implication

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Cite This Study

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