Association of disease awareness, medication adherence, and home blood pressure monitoring with blood pressure control in hypertensive patients: a cross-sectional study

Q: What are the key findings of this study?

Home blood pressure monitoring was independently associated with a reduced likelihood of uncontrolled hypertension (OR 0.48), alongside higher disease awareness and better medication adherence.

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Hypertension (n=280). Intervention: Home blood pressure monitoring (HBPM) vs. No home blood pressure monitoring. Primary outcome: Uncontrolled hypertension (OR 0.48, 95% CI 0.29-0.78, p=0.003).

Q: What does this research mean for the field?

Home blood pressure monitoring, higher disease awareness, and better medication adherence are independently associated with reduced likelihood of uncontrolled hypertension. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Murat Karamanlıoğlu

doi:10.32322/jhsm.1941289

July 20, 2026Journal of Health Sciences and MedicineOpen Access

Association of disease awareness, medication adherence, and home blood pressure monitoring with blood pressure control in hypertensive patients: a cross-sectional study

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Key result

Home blood pressure monitoring is linked to ~52% lower odds of uncontrolled hypertension.

OR 0.48
95% CI 0.29-0.78
P=0.003
n=280

Why the study?

Hypertension remains a major global health problem with challenging blood pressure control, prompting evaluation of the relationship between blood pressure control and patient-related factors including disease awareness, medication adherence, and home blood pressure monitoring.

Are disease awareness, medication adherence, and home blood pressure monitoring associated with blood pressure control in hypertensive patients?

Key Points

To evaluate the relationship between disease awareness, medication adherence, home blood pressure monitoring behaviors, and blood pressure control in patients with hypertension.
Conducted a prospective, single-center, cross-sectional study evaluating N=280 adult patients with hypertension.
Assessed disease awareness with the Hypertension Knowledge-Level Scale (HK-LS), medication adherence with the Adherence to Refills and Medications Scale (ARMS), and home blood pressure monitoring (HBPM) habits via a structured questionnaire.
Performed multivariable logistic regression, receiver operating characteristic analysis, calibration plots, and decision curve analysis to identify independent predictors of uncontrolled hypertension.
Uncontrolled hypertension occurred in 132 of 280 patients (47.1%), while 148 patients (52.9%) had controlled hypertension.
Patients with controlled hypertension had significantly higher HK-LS awareness scores (17.8±2.6 vs. 14.9±3.1, p<0.001) and lower ARMS non-adherence scores [18 (15-22) vs. 25 (20-30), p<0.001] compared to those with uncontrolled hypertension.
Performing HBPM was significantly more common in the controlled group than in the uncontrolled group (75.7% vs. 47.0%, p<0.001), as was regular monitoring at least three times per week (58.1% vs. 28.8%, p<0.001).

Study Design

Type

Cross-Sectional (n=280)

Multicenter

No

Structured PICO

Are disease awareness, medication adherence, and home blood pressure monitoring associated with blood pressure control in hypertensive patients?

P

Population

280 adult patients with essential hypertension on medication for at least 3 months were evaluated in a cross-sectional study to identify predictors of uncontrolled blood pressure.

O

Outcome

Blood pressure control status (controlled vs. uncontrolled HT based on office BP measurements in accordance with current guideline-recommended thresholds)surrogate

Main Result

Odds Ratio: 0.48 (95% CI 0.29–0.78)

p-value: p=0.003

Limitations

Single-center design may limit generalizability
Cross-sectional nature precludes causal inference
Self-reported data for medication adherence and HBPM habits may be subject to recall bias
Potential confounders such as socioeconomic status, health system factors, and psychological variables were not assessed
Detailed information regarding specific antihypertensive treatment regimens was not systematically collected

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Implication

Disease awareness, medication adherence, and home blood pressure monitoring are independent predictors of blood pressure control in hypertensive patients, highlighting the importance of patient-centered management strategies.

Abstract

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Discussion

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Cite This Study

Murat Karamanlıoğlu (2026) conducted a cross-sectional in Hypertension (n=280). Home blood pressure monitoring (HBPM) vs. No home blood pressure monitoring was evaluated on Uncontrolled hypertension (OR 0.48, 95% CI 0.29-0.78, p=0.003). Home blood pressure monitoring was independently associated with a reduced likelihood of uncontrolled hypertension (OR 0.48), alongside higher disease awareness and better medication adherence.

synapsesocial.com/papers/6a6e12232163a0a01bc31193 https://doi.org/10.32322/jhsm.1941289

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Association of disease awareness, medication adherence, and home blood pressure monitoring with blood pressure control in hypertensive patients: a cross-sectional study

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Association of disease awareness, medication adherence, and home blood pressure monitoring with blood pressure control in hypertensive patients: a cross-sectional study

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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