Multistakeholder workshop identifies integration challenges and opportunities for NAMs in risk assessment and safety design.
Key Points
The aim is to explore how New Approach Methodologies (NAMs) can be integrated into Next-Generation Risk Assessment (NGRA) and Safe-and-Sustainable-by-Design (SSbD) frameworks.
Conducted a multistakeholder workshop in October 2025 with researchers, risk assessors, and industry representatives.
Discussed the operationalization challenges and potential solutions for integrating NAMs into regulatory and innovation contexts.
Emphasized the importance of initial safety assessments using physiochemical properties and (Q)SAR models.
Identified major challenges like establishing decision frameworks for further testing in the safety evaluation processes.
Recommended cross-sector collaboration to foster mutual learning and harmonization in the implementation of NAMs.
Advocated for reliable NAMs that cater to varying confidence levels needed in NGRA compared to SSbD.