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July 24, 2026Nano ConvergenceOpen Access

New approach methodologies for next-generation risk assessment of nanomaterials and nano-enabled products

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Authors

ELEunseo LeeACAline CharyZGZayakhuu Gerelkhuu

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Overview

Review analyzes new approach methodologies for nanosafety assessment, highlighting regulatory challenges and advancements.

Key Points

  • This review evaluates the integration of innovative technologies for risk assessment of nanomaterials, focusing on NAMs and regulatory implications.
  • Comprehensive analysis of advanced test systems including organoids and microphysiological systems.
  • Review of regulatory frameworks across Europe, Africa, the Americas, and Asia-Pacific.
  • Discussion on implementation of NAMs in various industries and future directions like Smart NAMs.
  • Highlights the need for robust physicochemical characterization and reproducibility for regulatory acceptance.
  • Identifies pathways for harmonizing risk assessment with a focus on biological relevance and data interoperability.
  • Emphasizes the role of Smart NAMs and Safe and Sustainable by Design frameworks for future assessments.

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/6a6301a6395161722cd162e1https://doi.org/10.1186/s40580-026-00566-w
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