Demonstrates enhanced bioconjugation through sulfo-click reaction, indicating broad applications in medicinal chemistry.
The sulfo-click reaction, which relies on the chemoselective coupling of sulfonyl azides with thioacids to yield Nacylsulfonamides, has emerged as a powerful and versatile transformation in synthetic chemistry and bioconjugation....
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Smietana et al. (2026) studied this question.
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