Key result
Routine echocardiography after cardiac surgery reveals a ~36% incidence of pericardial effusion.
Why the study?
Reported incidences of postoperative pericardial effusion range widely from 2% to 85%, and while most resolve spontaneously, a subset progresses to cardiac tamponade requiring urgent intervention.
What is the incidence of postoperative pericardial effusion and the need for reintervention in patients undergoing cardiac surgery?
Meta-Analysis (n=8,495)
What is the incidence of postoperative pericardial effusion and the need for reintervention in patients undergoing cardiac surgery?
Postoperative pericardial effusion is common (36%) after cardiac surgery, but only a small fraction (3%) require reintervention, though large effusions (>2 cm) significantly increase this risk.
Low reintervention rates support selective post-cardiac surgery echocardiography; extends prior estimates with contemporary pooled data.
Postoperative pericardial effusion (PPE) is a common finding after cardiac surgery, with reported incidences ranging widely from 2% to 85%. While most effusions resolve spontaneously, a subset progresses to cardiac tamponade requiring urgent intervention. This systematic review evaluated the true incidence of PPE and PPE-related reinterventions based on routine echocardiographic screening, and explored temporal evolution, symptomatology, and perioperative risk factors. A comprehensive search of Embase, PubMed, and Web of Science through May 2025 identified 26 eligible studies including 8,495 patients. Data extraction followed PRISMA guidelines and quality assessment with the JBI checklist. Random-effects meta-analysis demonstrated a pooled PPE incidence of 36% (95% confidence interval (CI) 25-49%), whereas only 3% (95% CI 2-4%) required reintervention, ranging from 2% after CABG to 6% after aortic surgery. Large effusions (> 2 cm) were associated with a substantially higher likelihood of intervention (54% [14-90%]), although spontaneous resolution remained common. Preventive strategies such as posterior pericardiotomy and posterior chest tube placement significantly reduced both PPE incidence and reintervention rates. Despite these findings, interpretation is limited by substantial heterogeneity in study design, definitions, and follow-up protocols. Standardized definitions, structured echocardiographic follow-up, and prospective studies are needed to improve risk stratification and guide clinical decision-making.
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Dinter et al. (2026) conducted a meta-analysis in Postoperative pericardial effusion (n=8,495). Cardiac surgery was evaluated on Pooled incidence of postoperative pericardial effusion (PPE) (95% CI 25-49). Routine echocardiography after cardiac surgery revealed a pooled postoperative pericardial effusion incidence of 36%, with 3% of patients requiring reintervention.
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