Case Report on Pemphigoid Gestationis: A Rare Autoimmune Disease in Pregnancy

The rare autoimmune bullous disease, pemphigoid gestationis (PG), is exclusively associated with pregnancy.It typically appears in the second or third trimester of pregnancy and is linked to problems for both the mother and the fetus.It seriously damages the skin's basement membrane, which leads to severe itching and blisters on the belly and limbs.Here, we present the successful management of a 32-year-old woman with PG who was 22 weeks pregnant using systemic steroids, leading to a positive result.Given the disease's rarity, we wanted to report a case of early PG diagnosis based on the distinctive clinical presentation, which was then corroborated by skin biopsy and histopathology.Systemic corticosteroid treatment was administered, and hospitalization was required during an acute exacerbation.It was necessary for dermatologists and gynecologists to consult together.Prematurity, small-for-date infants, oligohydramnios, and gestational diabetes mellitus all affected the pregnancy.