What does this research mean for the field?

Lotus seed extracts, particularly those obtained via ultrasonic-assisted extraction, exhibit significant antioxidant and antidiabetic properties, while Soxhlet extracts demonstrate stronger antimicrobial activity, making them promising candidates for functional foods and phytopharmaceuticals. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to evaluate the phytochemical composition and various biological activities of lotus seed extracts.

June 7, 2026Chemistry & Biodiversity

Integrated In Vitro and In Silico Evaluation of Lotus ( Nelumbo nucifera ) Seed Extracts for Antioxidant, Antimicrobial, and Antidiabetic Potentials

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Authors

SCShiwa ChaubeyNational Botanical Research Institute KSKhuraijam Jibankumar SinghNational Botanical Research Institute MSManjoosha SrivastavaNational Botanical Research Institute

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Implication

Randomized trial evaluates antioxidant, antimicrobial, and antidiabetic activities of lotus seed extracts, indicating their potential for health applications.

Key Points

The aim is to evaluate the phytochemical composition and various biological activities of lotus seed extracts.
Utilized Soxhlet and ultrasonic-assisted extraction methods with methanol.
Assessed antioxidant, antimicrobial, and antidiabetic activities.
Performed UHPLC-DAD analysis to identify phytochemicals.
The ultrasonic extract yielded higher phenolic (107.92 mg GAE/g) and flavonoid (104.89 mg QE/g) contents than the Soxhlet extract.
The UL extract exhibited antioxidant activity with an IC50 of 17.51 µg/mL, and enzyme inhibition for α-amylase with an IC50 of 12.54 µg/mL.
The SL extract demonstrated stronger antimicrobial activity, with a MIC of 1.0 mg/mL against Staphylococcus aureus.

Cite This Study

Chaubey et al. (2026) studied this question.

synapsesocial.com/papers/6a250c957def13d035e1cbbc https://doi.org/10.1002/cbdv.202503151

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Implication

Randomized trial evaluates antioxidant, antimicrobial, and antidiabetic activities of lotus seed extracts, indicating their potential for health applications.

Integrated In Vitro and In Silico Evaluation of Lotus ( Nelumbo nucifera ) Seed Extracts for Antioxidant, Antimicrobial, and Antidiabetic Potentials

Discussion

Member takes

Implication

Key Points

Cite This Study

Integrated In Vitro and In Silico Evaluation of Lotus ( Nelumbo nucifera ) Seed Extracts for Antioxidant, Antimicrobial, and Antidiabetic Potentials

Discussion

Member takes

Implication

Key Points

Cite This Study

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